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我们在1989年4~10月间试用利福平胶囊治疗难治性菌痢20例,在临床上获得满意的效果。临床资料病例选择符合《1977年吉林省菌痢防治方案》的标准。20例患者,男12例,女8例。年龄11个月~61岁,<5岁11例(55%)。均在本科或院外用SMZ、吡哌酸、庆大霉素和丁胺卡那等治疗,病程10~20天。而临床症状仍明显。粪便培养出痢疾杆菌14例(福氏菌9例,宋氏菌2例,混合菌3例)。伴脱水者7例。治疗方法:成人每日900mg或儿童按每日10~20mg/kg分二次空腹口服,同时配用T.M.P口服。
We trial in April to October 1989 rifampin capsules treatment of refractory bacillary dysentery in 20 cases, clinically satisfactory results. Clinical data The case selection in line with “1977 Jilin Province dysentery prevention and control program” standard. 20 patients, 12 males and 8 females. Age 11 months to 61 years old, <5 years old in 11 cases (55%). All undergraduate or hospital with SMZ, pipemidic acid, gentamicin and amikacin treatment, the duration of 10 to 20 days. The clinical symptoms are still obvious. Stool culture dysentery bacilli in 14 cases (9 Fungi, Song Song 2, mixed bacteria in 3 cases). 7 cases with dehydration. Treatment: 900mg daily for adults or children per day 10 ~ 20mg / kg points twice fasting, oral administration with T.M.P.