氨氯地平是一种新型的二氢吡啶类钙通道阻滞剂,口服后血药浓度达峰时间约为6～12h,绝对生物利用度64～80%。终末消除半衰期约为35～50h,现已成为临床治疗心绞痛、高血压的重要药物,最常见的副作用是头痛。水肿、疲劳、恶心、腹痛、潮红、心悸或眩晕。目前,国内有多个厂家生产氨氯地平片,这给临床选用带来一定的困难, Amlodipine is a new type of dihydropyridine calcium channel blockers, oral administration of plasma concentration peak time is about 6 ~ 12h, the absolute bioavailability of 64 to 80%. Terminal elimination half-life of about 35 ~ 50h, has now become clinically important for the treatment of angina pectoris, hypertension, the most common side effects are headache. Edema, fatigue, nausea, abdominal pain, flushing, palpitations or dizziness. At present, there are a number of domestic manufacturers of amlodipine tablets, which bring some difficulties for clinical use,