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本文对74例恶性黑色素瘤(MM)在光镜下从不同角度做了分型。13例做了电镜观察,其中5例有转移瘤。原发性和转移性无色素性 MM 均显示较强的 S-100蛋白阳性反应。观察表明,电镜检查和 S-100蛋白染色对 MM 的病理诊断有确定价值,尤其对无黑色素性 MM 的确诊尤为重要。并提出了电镜诊断 MM 的最低诊断标准。
In this paper, 74 cases of malignant melanoma (MM) were classified under light microscope from different angles. Electron microscopy was performed in 13 cases, of which 5 cases had metastases. Both primary and metastatic non-pigmented MM showed strong S-100 protein positive reaction. Observations have shown that electron microscopy and S-100 protein staining are of definite value in the pathological diagnosis of MM, especially in the diagnosis of amelanotic MM. And proposed the minimum diagnostic criteria for electron microscopy diagnosis of MM.