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目的探讨机械通气和吗啡联合治疗重症急性左心衰竭的疗效及临床价值。方法选择2001年5月～2004年7月在我院住院治疗的重症急性左心衰患者62例,其中36例在常规药物治疗的基础上,予以机械通气及吗啡联合治疗(观察组),另26例仅给予常规药物治疗(对照组)。比较两组的疗效及死亡率,比较机械通气前后血气变化。结果观察组有效率明显高于对照组,病死率明显低于对照组(P<0.05),机械通气前后血气改善明显(P<0.01或P<0.05)。结论机械通气联合吗啡是重症急性左心衰积极、有效的治疗措施。
Objective To investigate the efficacy and clinical value of mechanical ventilation and morphine in the treatment of severe acute left heart failure. Methods Sixty-two patients with severe acute left heart failure who were hospitalized in our hospital from May 2001 to July 2004 were selected. Among them, 36 patients were treated with mechanical ventilation and morphine (observation group) on the basis of conventional medical therapy. Twenty-six cases were given only conventional medication (control group). Efficacy and mortality of the two groups were compared, and blood gas changes before and after mechanical ventilation were compared. Results The effective rate of the observation group was significantly higher than that of the control group, and the mortality was significantly lower than that of the control group (P <0.05). The improvement of blood gas was obvious before and after mechanical ventilation (P <0.01 or P <0.05). Conclusion Mechanical ventilation combined with morphine is a positive and effective treatment for severe acute left heart failure.