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目的了解东莞市流动人口妇女宫颈人乳头瘤病毒(HPV)感染及基因型情况,分析探讨HPV感染的影响因素,为预防HPV和宫颈癌提供基础资料。方法收集东莞市32个镇区18~69岁年龄段10 901人进行HPV检查和问卷调查。对HPV阳性者进行HPV分型。问卷调查内容包括基本信息、月经婚育史、性行为及避孕史等。结果所有检查对象中,HPV感染698例,感染率为6.40%,感染率最高的亚型为HPV16型共162例,感染率1.49%,其他依次为52型(127例,感染率1.17%)、58型(95例,感染率0.87%);单因素分析HPV感染的危险因素与年龄、职业、文化程度、性伴侣数、性生活年限、分娩流产次数等有关;多因素分析结果表明,性伴侣数、分娩流产次数为影响HPV感染的独立危险因素。结论东莞市流动人口妇女HPV常见的亚型依次为HPV16、52、58型,性伴侣数、分娩流产次数为影响HPV感染的独立影响因素。对人群进行高危型HPV感染筛查能有效地防治宫颈癌,有良好的社会经济效益。
Objective To understand the status of HPV infection and genotypes among migrant women in Dongguan City and to explore the influencing factors of HPV infection so as to provide the basic information for the prevention of HPV and cervical cancer. Methods A total of 10 901 people aged 18-69 in 32 townships of Dongguan City were collected for HPV test and questionnaire survey. HPV-positive HPV typing. Questionnaire content includes basic information, menstrual marriage history, sexual behavior and contraception history. Results Among all the test subjects, HPV infection was 698 and the infection rate was 6.40%. The highest infection rate was HPV16 type with 162 cases, the infection rate was 1.49%, the other was 52 (127 cases, infection rate 1.17%), 58 (95 cases, infection rate 0.87%); univariate analysis of risk factors for HPV infection and age, occupation, education level, number of sexual partners, sexual life, the number of abortion and so on; multivariate analysis showed that sexual partners The number of abortion is the number of independent risk factors affecting HPV infection. Conclusion The common subtypes of HPV in migrant women in Dongguan are HPV16, 52 and 58, the number of sexual partners and the number of abortions are the independent influencing factors of HPV infection. High-risk HPV infection screening of the crowd can effectively prevent and treat cervical cancer, have good social and economic benefits.