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目的观察雷贝拉唑联合威地镁治疗反流性食管炎的临床疗效。方法126例经内镜确诊的反流性食管炎,采用配对分组法分为三组,A组43例:口服雷贝拉唑20 mg,2次/d,口服威地镁1 g,3次/d;B组42例,口服雷贝拉唑20 mg 2次/d;C组41例,口服威地镁1 g,3次/d。疗程共8周。结果A、B、C三组总有效率分别为93.0%,73.8%和68.3%。内镜下病变改善总有效率分别为97.7%,78.6%和61.0%。结论雷贝拉唑联合威地镁治疗反流性食管炎症状改善迅速,病变治愈率也高,临床疗效优于单用雷贝拉唑或单用威地镁。
Objective To observe the clinical efficacy of rabeprazole combined with weilamag in the treatment of reflux esophagitis. Methods 126 cases of reflux esophagitis diagnosed by endoscopy were divided into three groups according to the method of pairing group A, 43 cases in group A: oral rabeprazole 20 mg, twice a day, oral WeiDi magnesium 1 g, 3 times / d; Group B, 42 patients, oral rabeprazole 20 mg twice a day; Group C, 41 patients, oral Wei magnesium 1 g, 3 times / d. Treatment for a total of 8 weeks. Results The total effective rates of A, B and C groups were 93.0%, 73.8% and 68.3% respectively. The total effective rate of endoscopic lesion improvement was 97.7%, 78.6% and 61.0% respectively. Conclusion Rabeprazole combined with Granville Magnesium in the treatment of reflux esophagitis symptoms improved rapidly, the cure rate is also high, the clinical efficacy is superior to rabeprazole alone or alone Granville.