论文部分内容阅读
毛圆线虫敏感株和抗药株表型的相对适应性是影响虫体对驱虫药抗性的主要因素之一。以往对两株的适应性比较研究,未能得出明确结论。这些研究主要集中在寄生虫生物学和宿主体内致病作用的差异,迄今尚无关于成虫生理学或宿主肠道炎症反应株特异性变异方面的资料。本文用羊的蛇形毛圆线虫的噻苯达唑抗性株和敏感株各5000条感染期幼虫感染家兔,体外测试成虫乙酰胆碱酯酶(AChE)的分泌以反映虫体生理学特点,用小肠粘膜匀浆中过氧化物酶活性及肥大细
The relative adaptability of T. gonorrhoeae sensitive strains and resistant strains phenotype is one of the main factors that affect the resistance of insect to deworming. The past two strains of the comparative study of flexibility, failed to draw a clear conclusion. These studies have focused mainly on the differences in the biology of the parasite and the pathogenic effects in the host, and so far no data have been available on the physiology of the adult or the specific variation of the host intestinal inflammatory response. In this paper, the sheep infected with thiabendazole resistant strains and sensitive strains of T. gondii were infected with 5000 larvae each in vitro. The secretion of acetylcholinesterase (AChE) was measured in vitro to reflect the physiological characteristics of the parasites. Mucosal homogenate peroxidase activity and mast cell size