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目的 探讨肺癌病人肿瘤标记物的阳性率及对肺癌诊断的意义。方法 不同期别、组织类型的肺癌病人70例,分别测定其神经原特异性烯醇化酶(NSE)、癌胚抗原(CEA)、铁蛋白和β_2微球蛋白(β_2MG),并将四种标记物进行组合。结果 NSE对小细胞肺癌的特异性最强,四项标记物联合检测的阳性率最高。结论 肺癌标记物联合检测可以互相弥补缺陷,提高肺癌的诊断率,并帮助判定病期及病理类型。
Objective To investigate the positive rate of tumor markers in lung cancer patients and its significance in the diagnosis of lung cancer. Methods Seventy patients with lung cancer of different stages and types were tested for neuroendocrine-specific enolase (NSE), carcinoembryonic antigen (CEA), ferritin and β_2 microglobulin (β_2MG), and the four markers Things are combined. Results NSE showed the strongest specificity for small cell lung cancer and the highest positive rate of four markers combined detection. Conclusions Combined detection of lung cancer markers can make up for the defects of each other, improve the diagnostic rate of lung cancer and help determine the stage and pathological type.