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[病例] 女性,43岁,因间断腹痛、口腔、阴唇粘膜溃疡10年入院。5年前出现腹泻,时有血性粘液便,自服氯毒素、黄连素等药,症状能缓解。近1年来,腹痛加重,下腹部由针刺样痛转为持续性胀痛,间断发热,体温在37℃～38℃之间。近日来头晕乏力、多汗、消瘦,食欲不振。另外,与腹痛伴行症状有舌、口唇、阴唇及肛门周围粘膜反复发生痛性溃疡。10年前诊断骨髓纤维化。查体:轻度贫血貌,颌下及左颈前可触到数个黄豆粒大小淋巴结,活动度好,无触痛。肝大右锁骨中线助弓下3.0cm,质硬。脾肿大甲乙线
[Case] Female, 43 years old, due to intermittent abdominal pain, mouth, labia mucosal ulcer 10 years admitted. 5 years ago, diarrhea, bloody mucus, spontaneously chlorotoxin, berberine and other drugs, the symptoms can be alleviated. Over the past year, abdominal pain increased, the lower abdomen acupuncture-like pain into persistent pain, intermittent fever, body temperature between 37 ℃ ~ 38 ℃. In recent days, dizziness, fatigue, sweating, weight loss, loss of appetite. In addition, accompanied by symptoms of abdominal pain tongue, lips, labia and mucosa around the anal recurrent pain ulcer. 10 years ago to diagnose myelofibrosis. Physical examination: mild anemia appearance, submandibular and left neck before touching several soybean size lymph nodes, good activity, no tenderness. Big right supraclavicular midline help bow 3.0cm, hard. Splenomegaly A line