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由Ee-Tor生物型霍乱弧菌引起,累及三个洲许多国家的第七次霍乱世界性流行,揭示了霍乱带菌者在传播本病中起了作用。应用现时的霍乱菌苗除了不能控制带菌者外,也不能长时期提供明显的予防霍乱的效果,这导致了许多学者考虑用化学予防法以控制霍乱的传播。 De等最近使用强力霉素治疗病人。他们所采用的三种剂量中,发现口服一剂300毫克强
Caused by the Vibrio cholerae Ee-Tor biotype, which affects the seventh worldwide cholera epidemic in many countries in all three continents, it is revealed that cholera carriers play a role in the transmission of this disease. The application of the current cholera vaccine can not provide significant cholera control effect over a long period of time, except that it can not control carriers. This has led many scholars to consider using chemical prophylaxis to control the spread of cholera. De et al recently used doxycycline to treat patients. Three of the doses they used were found to be orally administered as a 300 mg strong