论文部分内容阅读
目的 通过对急性PQ中毒治疗方法的分析探讨其疗效.方法将2013年1月-2015年12月第四军医大学西京医院收治的221例急性PQ口服中毒患者甲基强的松龙和环磷酰胺的治疗方案、是否行血液净化治疗的疗效进行对比分析.结果①服毒剂量>5 mL行血液净化治疗的急性PQ患者死亡率均低于未行血液净化治疗的中毒患者(P0.05).结论 急诊PQ中毒救治疗效与服毒剂量密切相关.“,”Objective To evaluate the clinic efficacy by analyzing the different treatment methods of acute paraquat poisoning. Methods Clinical data of 221 paraquat-poisoned patients admitted into the emergency department was recorded, and the therapies of Methylprednisolone and cyclophosphamide combined with blood purification were retrospectively analysis. Results ①When the toxic dose was larger than 5ml, the mortalities of paraquat-poisoned patients in the treatment of blood purification were significantly lower than the patients without the treatment of blood purification(P<0.01).②When the toxic dose was between 5 and 50ml, the mortalities of patients in the groups of methylprednisolone combined cyclophosphamide were obviously lower than than the patients in the groups of methylprednisolone(P<0.05). When the toxic dose was between 50 and 100ml, the mortality of patients in the groups of methylprednisolone was markedly lower than the patients in the groups of methylprednisolone combined cyclophosphamide(P0.05).Conclusion Different methods were alternatively chosen closely related to the toxic dose in the treatment of acute paraquat poisoning.