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对象:1.研究组:80例不明原因晕厥病人。2.对照组:13例无晕厥病史正常人。倾斜试验(TTT)方案:采用倾斜70度最长观察30分钟(BTTT),继之静滴异丙肾上腺素(ISO)1~5μg/分钟,仍倾斜70度最长观察30分钟(ITTT)。结果:1.研究组和对照组基础心率和血压差异无显著性(p>0.05)。2.研究组TTT阳性51例,其中BTTT阳性18例,ITTT阳性33例,ISO平均用量2.31±0.82μg/分钟,在ITTT阳性者中仅1例ISO用量达4μg/分钟。3.对照组13例,1例ITTT阳性。ISO平均用量2.77±1.3μg/分钟,ISO用量与研究组比较差异无显著(p>0.05)。结论:本试验结果的敏感性为63.8%,特异性92.3%。合用异丙肾上腺素使TTT阳性率明显提高,但异丙肾上腺素用量以不大于3μg/分钟为宜。
Objects: 1. Study Group: 80 patients with unexplained syncope. 2. Control group: 13 cases without syncope history of normal people. Tilting Test (TTT): Tilting at a maximum of 70 degrees for 30 minutes (BTTT), followed by intravenous infusion of isoproterenol (ISO) at 1 to 5 μg / minute and an inclination of 70 degrees for a maximum of 30 minutes (ITTT). Results: 1. There was no significant difference in basal heart rate and blood pressure between study group and control group (p> 0.05). 2. In the study group, TTT was positive in 51 cases, of which 18 were BTTT positive, 33 were ITTT positive, and the average ISO dosage was 2.31 ± 0.82 μg / min. Only 1 patient with ITTT positive had an ISO dosage of 4 μg / min. 3. Control group, 13 cases, 1 case of ITTT positive. The average ISO dosage was 2.77 ± 1.3μg / min. There was no significant difference in ISO dosage between the two groups (p> 0.05). Conclusion: The results of this test were 63.8% with a specificity of 92.3%. Combination of isoproterenol TTT positive rate was significantly increased, but the amount of isoproterenol to not more than 3μg / min is appropriate.