本试验采用暴露糖代谢中间产物的方法,以葡萄糖负荷试验,在正常及去肾上腺大鼠一次注射大剂量可的松后测定不同时间內血糖、血丙酮酸、肌糖元及肝糖元的变化。通过这些变化与时间的关系初步阐明:(1) 可的松对肝、肌糖元的沉积作用;(2) 肝糖元沉积的前身物质的可能来源;(3) 可的松对丙酮酸及葡萄糖水平的影响。借此,探讨可的松对糖代谢作用的可能机制。 In this study, glucose metabolism was used to measure the changes of blood glucose, blood pyruvate, muscle glycogen and hepatic glycogen in different time after one-time injection of cortisone in normal and adrenal rats . Through the relationship between these changes and time, we initially clarified: (1) the deposition of cortisone on liver and muscle glycogen; (2) the possible source of pre-glycogen deposition; (3) cortisone on pyruvate and Effects of glucose levels. To explore the possible mechanism of cortisone on glucose metabolism.