熔点、熔化焓和熔化熵是化合物的重要的热力学参数。本工作首次报道了一系列β位取代桂皮酰胺类化合物的这些热力学参数。由于桂皮酰胺类化合物具有抗癫癎、镇惊活性,因此,对该类化合物的结构和功能的研究,已成为人们感兴趣的研究课题。文献上报道的通常是化合物的油水分配系数、取代基常数、基团偶极矩和诱导效应指数等参数与抗惊活性的关 Melting point, enthalpy of fusion and entropy of melting are important thermodynamic parameters of the compound. This work reported for the first time a series of β-substituted cinnamic amide compounds of these thermodynamic parameters. Because cinnamide compounds have antiepileptic and anticonvulsant activity, studies on the structure and function of these compounds have become the research topics of interest. Reported in the literature is usually compound oil and water partition coefficient, substituent constants, group dipole moment and induced effect index and other parameters and anti-shock activity