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[目的]果蝇伴性隐性致死试验观察食用油烟雾(FEO)和食用油加热剩油(CEO)的致突变作用。[方法]分别用FEO(110、320、960μg/ml)和CEO(416、833、1667μg/ml)的3个不同浓度喂饲果蝇对其细胞的遗传毒性进行研究。[结果]320μg/ml浓度组的FEO第Ⅰ、Ⅱ、Ⅲ窝致突变率分别达到0.257%、0.530%和0.506%(P<0.001);110μg/ml浓度组的第Ⅰ窝和960μg/ml浓度组的第Ⅰ、Ⅱ窝与对照组相比差异有显著性(P<0.001)。所有CEO浓度组的伴性隐性致死试验结果都呈阳性(P<0.001),但未见剂量-反应关系。[结论]FEO和CEO对雄性黑腹果蝇具有较高的毒性作用。
[Objective] To investigate the mutagenicity of die-associated recessive lethal test in edible oil fuels (FEO) and edible oils (CEO). [Method] The genetic toxicity of Drosophila fed with three different concentrations of FEO (110,320,960μg / ml) and CEO (416,833,1667μg / ml) on their cells were studied. [Results] The mutagenicity rates of FEO Ⅰ, Ⅱ and Ⅲ in the 320μg / ml group were 0.257%, 0.530% and 0.506%, respectively (P <0.001); the first and the 960μg / ml concentrations in the 110μg / ml group Group Ⅰ, Ⅱ litter compared with the control group, the difference was significant (P <0.001). All of the Cloosteo-ID patients in the CEO concentration group had positive CCT (P <0.001) but no dose-response relationship. [Conclusion] FEO and CEO have higher toxicity to male Drosophila melanogaster.