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躯体内脏相关和脊神经节的核团性质是感觉神经科学领域的两个热点课题,前者的关键在于是否存在既接受躯体感觉信息又接受内脏感觉信息的躯体觉/内脏觉会聚性神经元;后者的关键是脊神经节内是否存在突触/接头性活动。如同将运动神经元区分为躯体运动性神经元和内脏(自主)运动性神经元那样,人们迄今一直认为,感觉神经元分为躯体感觉性神经元和内脏(自主)感觉性神经元,分别支配躯体和内脏(Kandel 1991)。与躯体觉的传入通路有别,内脏传入的胞体可追踪到脊髓Ⅰ,Ⅱ,Ⅳ,Ⅴ和Ⅹ板层,内脏感觉信息的上行通路只限于背索(DC)、脊丘束(STT)和脊网束(Willis 1991,Ness和Gebhart 1990)。另一方面,脊神经节被定义为躯体感觉系统的感受器(Kandel 1991),一向被视为一种感觉传入通路的简单集合和感觉纤维营养物质的贮存站,甚至认为其在感觉信息传入中的作用可有可无(Liberman 1976)。根据我们近年对脊髓投射系统和脊神经节的研究以及国内外有关学者的工作,上述传统认识似有很大的局限性。
Somatic visceral and spinal ganglion nuclei are two hot topics in the field of sensory neuroscience. The former is based on the existence of somatic / visceral convergent neurons that both receive somatosensory and visceral sensory information. The latter The key is whether there is synaptic / linker activity in the spinal ganglia. So far, it has been thought that somatic motor neurons are divided into somatic motor neurons and visceral (autonomous) motor neurons, and sensory neurons are divided into somatosensory neurons and visceral (autonomous) sensory neurons, respectively Body and internal organs (Kandel 1991). Which is different from the somatosensory afferent pathway. The visceral afferent cell bodies can be traced to Ⅰ, Ⅱ, Ⅳ, Ⅴ and Ⅹ layers of the spinal cord. Upstream pathways of visceral sensory information are confined to DC, ) And spinal bundles (Willis 1991, Ness and Gebhart 1990). On the other hand, the dorsal root ganglia, defined as the sensor of the somatosensory system (Kandel 1991), has long been regarded as a simple collection of sensory afferent pathways and as a storage depot for sensory fiber nutrients, even as a sensory input Optional (Liberman 1976). According to our recent studies on the spinal cord projection system and spinal ganglia as well as the work of scholars at home and abroad, the above traditional understanding seems to have great limitations.