论文部分内容阅读
目的探究限制补液策略对结直肠癌伴糖尿病患者术后早期康复的临床价值。方法回顾性研究2007年1月至2009年10月期间四川大学华西医院结直肠外科专业组收治的伴糖尿病的结直肠癌患者的临床资料,分析比较采用不同补液方案(限制补液组和常规补液组)的术后首次排气、进食、下床活动及住院时间,术后早期并发症(伤口感染、吻合口漏、肠梗阻),生化与血常规检查指标(血红蛋白、白细胞计数、葡萄糖、尿素氮)。结果限制补液组术后首次排气及下床活动时间均早于常规补液组(P<0.05),而2组术后首次进食、术后住院时间的差异无统计学意义(P>0.05)。在术后早期并发症方面,限制补液组的伤口感染率明显低于常规补液组(P<0.05),而2组间吻合口漏及肠梗阻发生率差异无统计学意义(P>0.05)。生化与血常规检查指标,术前2组患者各指标的差异均无统计学意义(P>0.05);术后限制补液组葡萄糖水平明显低于常规补液组(P<0.05),其余指标2组间差异无统计学意义(P>0.05)。结论术后限制补液策略可以降低伴糖尿病的结直肠癌患者术后常见并发症的发生率并有利于患者的康复。
Objective To investigate the clinical value of restriction rehydration strategy in early postoperative rehabilitation of patients with colorectal cancer and diabetes mellitus. Methods The clinical data of patients with colorectal cancer with diabetes mellitus admitted to West China Hospital of Sichuan University from January 2007 to October 2009 were retrospectively analyzed. The clinical effects of different rehydration regimens (limited rehydration group and conventional rehydration group ), The first postoperative exhaust, feeding, ambulation and hospital stay, early postoperative complications (wound infection, anastomotic leakage, intestinal obstruction), biochemical and blood tests (hemoglobin, white blood cell count, glucose, urea nitrogen ). Results The duration of first extubation and ambulation after rehydration group was earlier than that of conventional rehydration group (P <0.05). However, there was no significant difference in postoperative hospital stay between the two groups (P> 0.05). In terms of early postoperative complications, the wound infection rate in the limited rehydration group was significantly lower than that in the conventional rehydration group (P <0.05). There was no significant difference in the incidence of anastomotic leakage and intestinal obstruction between the two groups (P> 0.05). (P> 0.05). There was no significant difference between the two groups before and after rehydration (P <0.05). The remaining indexes in group 2 There was no significant difference between the two groups (P> 0.05). Conclusion Postoperative rehydration strategy can reduce the incidence of postoperative complications and promote the recovery of patients with colorectal cancer.