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患者男性,63岁。因左小腿皮肤反复溃烂不愈10余年,以左胫骨慢性骨髓炎住院治疗。入院后准备施行左小腿病灶清除、肌皮瓣转移术。术前3天予氯霉素针剂lg加入5％葡萄糖盐水500ml中静滴抗感染,滴速40滴/min。约3min后,病人感胃部不适、恶心、全身皮肤出现红斑,继而大汗淋漓、胸闷、心悸。体检:神志清,面色潮红,呼吸24次/min,脉搏微弱,血压测不到,心律齐,心率136次/min,心前区未闻病理性杂音,两
Male patient, 63 years old. Repeated ulceration of the left calf skin due to healing more than 10 years to the left tibial chronic osteomyelitis hospitalized. After admission to prepare for the implementation of left calf lesions removal, myocutaneous flap transfer. Preoperative 3 days to chloramphenicol injection lg add 5% glucose saline 500ml intravenous anti-infection, drip 40 drops / min. About 3min later, the patient felt stomach discomfort, nausea, systemic skin erythema, then sweating, chest tightness, palpitations. Physical examination: conscious, flushing, breathing 24 times / min, weak pulse, blood pressure can not be measured, heart rate Qi, heart rate 136 beats / min, precordial no pathological murmurs, two