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α毒素是A型产气荚膜梭菌所致严重创伤性气性坏疽的主要致死因素，至今尚无有效的防治方法，使用抗生素和多价抗毒素效果不明显t‘J。为此，我们采用细胞融合技术，制备了抗a毒素的单克隆抗体（InAb），为治疗气性坏疽患者的a毒素中毒提供可能性。互材料和方法1．l抗原和细胞a?
Alpha toxin is the major lethal factor of severe traumatic gas gangrene caused by Clostridium perfringens type A. So far there is no effective prevention and treatment method. The effect of using antibiotics and polyvalent antitoxin is not obvious. To this end, we used monoclonal antibody (aAb) against a-toxin in cell fusion technology to provide a possibility for the treatment of a toxin poisoning in patients with gas gangrene. Mutual materials and methods 1. l Antigen and cell a?