目的:为1例脑梗死吞咽障碍口腔并发症的患者制订循证护理方案。方法:按PICO原则，针对患者临床表现提出问题，采用主题词和自由词相结合的方法，检索Uptodate、NICE、SIGN、RNAO、医脉通指南网、BMJ、Cochrane图书馆、PubMed、EMbase、CINAHL、中国知网等数据库，搜集有关脑梗死吞咽障碍患者口腔并发症的临床指南、系统评价和随机对照试验等，对证据评价后，将最适宜证据应用于该例患者并观察疗效。结果:共纳入1篇临床决策、5篇临床指南、4篇专家共识、2篇系统评价、1篇Meta分析、3篇RCT。根据检索结果并结合患者的病情及意愿，护士根据标准吞咽功能评定量表（SSA）内容每2日进行吞咽功能检查，进食时给予抬高床头40°~45°并保持1 h，每日3次用氯己定口腔护理液行负压冲洗法刷牙，用机械性擦洗法清除痰痂，每晚护士用6X刮舌技术擦洗舌背，感染得到控制后用0.9%氯化钠溶液每日2次冲洗刷牙。每日评估口腔情况及吞咽功能，用鼻面罩高流量湿化氧疗及面罩喷射雾化吸入等，入院后第3天行吞咽训练。证据应用于临床实践7 d后，患者口腔黏膜湿润无异味，无痰痂，吞咽功能由Ⅳ级变为Ⅱ级。结论:护理脑梗死吞咽障碍患者，护士要及时评估患者口腔及吞咽功能，应用氯已定及0.9%氯化钠溶液口腔护理液机械性擦洗法及负压冲洗式刷牙法能有效去除痰痂，用6X刮舌技术擦洗舌背，能减少微生物，减轻口臭；应用鼻面罩高流量湿化氧疗及喷射雾化吸入湿化效果显著，早期进行吞咽功能训练能减少口腔并发症的发生。“,”Objective:To develop an evidence-based nursing program for a patient with oral complications of dysphagia due to cerebral infarction.Methods:According to the principle of PICO, and the problem of patients' clinical manifestations, using the method of combining subject words and free words, the database of Uptodate, NICE, SIGN. RNAO, medical pulse guide network, BMJ, Cochranc library, PubMed, EMbase, CINAHL, China National Knowledge Infrastructure were searched and collected the clinical guidelines, systematic evaluation and randomized controlled trial of oral complications in patients with dysphagia of cerebral infarction.Results:Totally 1 clinical decision, 5 clinical guidelines, 4 expert consensus, 2 systematic evaluations, 1 Meta-analysis, 3 randomized controlled trial (RCT) were included. Based on the search results and the patient′s condition and wishes, nurses performed swallowing function tests every two days according to the Standard Swallowing function rating Scale (SSA), raised the head of the bed 40°~45° and holded it for 1 hour. Three times a day, the teeth were brushed with chlorhexidine oral care solution under negative pressure. Sputum scab was removed by mechanical scrubbing. The back of tongue was scrubbed by 6x tongue scraping technique every night. After the infection was controlled, the teeth were washed twice a day with 0.9% sodium chloride solution. Oral condition and swallowing function were evaluated daily. High flow humidification oxygen therapy and mask spray atomization inhalation were used. Swallowing training was performed on the third day after admission. Seven days after the evidence was applied to clinical practice, the oral mucosa was moist without peculiar smell and sputum scab, and the swallowing function was changed from grade IV to grade II.Conclusion:Nursing cerebral infarction patients with dysphagia, nurses should timely assess the patient's oral cavity and swallowing function, the application of chlorhexidine and 0.9% sodium chloride solution oral care solution mechanical scrubbing method and negative pressure washing brushing method can effectively remove sputum scab, use 6x tongue scraping technology to scrub the back of tongue, can reduce micro organisms, reduce halitosis; the application of nasal mask high flow humidification oxygen therapy and spray atomization inhalation humidification effect is obvious Therefore, early swallowing training can reduce the incidence of oral complications.