检查34名各种类型固体肿瘤患者的外周血淋巴细胞腺苷脱氨酶及乳酸脱氢酶的活性,发现肿瘤患者淋巴细胞内腺苷脱氨酶的活性低于正常人(P<0.01),而乳酸脱氢酶与正常人相比无统计学意义(P<0.1)。肝脏肿瘤患者及病变范围广泛者,淋巴细胞内的乳酸脱氢酶活力低于正常,P值分别小于0.05及0.01。这些酶的活性与肿瘤部位之间的关系不明显,而与肿瘤的广泛程度密切有关。病变范围广泛者其外围血淋巴细胞的两种酶活性低于正常人,而病变范围局限者这两种酶活性接近于正常人。 The activity of adenosine deaminase and lactate dehydrogenase in peripheral blood lymphocytes of 34 patients with various types of solid tumors was examined. The results showed that the activity of adenosine deaminase in lymphocytes was lower than that in normal people (P <0.01) However, lactate dehydrogenase had no statistical significance compared with normal subjects (P <0.1). Liver cancer patients and a wide range of lesions, lymphocyte lactate dehydrogenase activity was lower than normal, P values ​​were less than 0.05 and 0.01. The relationship between the activity of these enzymes and tumor sites is not obvious, but closely related with the extent of the tumor. The lesions of a wide range of peripheral blood lymphocytes of the two enzymes activity is lower than normal, and the lesion is limited to these two enzyme activity close to normal.