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【答】肝腺瘤样增生(AH)最初由Edmondson于1976年提出。它是肝脏在患急、慢性损害,尤其是肝硬变后所发生的一种类似肝细胞结节性增生,可见于胆管、门静脉和肝动脉等处。其增生的结节比肝硬变新生的结节明显增大,平均直径为8~10mm。最近,Nakanuma和Terada等根据细胞形态将AH分为两种类型:普通型和非典型前者肝细胞分化良好,无异型变;后者肝细胞有异型变。因此,非典型AH病例有时可见恶性病灶。Takayama等收集20例AH,其中18例随访6~50个月。在这18例中有9例发现结节增大
[Answer] Liver adenomatous hyperplasia (AH) was first proposed by Edmondson in 1976. It is a hepatocyte-like nodular hyperplasia that occurs in the liver after acute and chronic lesions, especially liver cirrhosis. It can be found in the bile duct, portal vein and hepatic artery. The hyperplastic nodule was significantly larger than the neonatal nodule with an average diameter of 8 to 10 mm. Recently, Nakanuma and Terada et al. divided AH into two types according to cell morphology: the common type and the atypical former had well differentiated hepatocytes without abnormal changes; the latter had heterotypic changes of hepatocytes. Therefore, malignant lesions are sometimes seen in cases of atypical AH. Takayama et al. collected 20 cases of AH, of which 18 cases were followed up for 6 to 50 months. In 9 of these 18 cases, nodules increased