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系统性红斑狼疮(systemic lupus erythematosus,SLE)是自身免疫性疾病的原型,发病机制十分复杂,至今仍不明确。近年研究表明,病毒感染可能是该病的一个重要的病因,病毒感染不仅参与SLE的发生发展,还与SLE的免疫学、临床表现有相关性。随着病毒感染与SLE相关性的研究深入,SLE的治疗也从中获得了一些启示。
Systemic lupus erythematosus (SLE) is a prototype of autoimmune diseases, the pathogenesis is very complex, is still not clear. Recent studies have shown that viral infection may be an important cause of the disease. Virus infection is not only involved in the development of SLE, but also related to the immunological and clinical manifestations of SLE. With the deep research on the correlation between virus infection and SLE, some enlightenment has been obtained from the treatment of SLE.