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目的 探讨35岁以下临床Ⅲ期乳腺癌的最佳治疗手段。方法 回顾分析139例35岁以下临床Ⅲ期乳腺癌的诊治过程。结果 全组5年生存率为35.25％,其中腋淋巴结无转移者5年生存率为52.38％,≥4个淋巴结转移者为22.64％(P<0.05);术后辅助化疗者的5年生存率是43.59％,单纯手术治疗组的5年生存率是24.53％(P<0.05);术后辅助放疗组局部复发率5.88％,单纯手术治疗组复发率33.96％(P<0.05)。结论 应积极开展早期手术结合化疗和放疗的综合治疗,这是目前达到提高生存质量,延长生存期的重要手段。
Objective To explore the best treatment for stage III breast cancer below 35 years old. Methods The clinical diagnosis and treatment of 139 patients with stage III breast cancer below 35 years old were retrospectively analyzed. Results The 5-year survival rate was 35.25% in the whole group. The 5-year survival rate was 52.38% in patients without axillary lymph node metastases, and 22.64% in patients with 4 or more lymph node metastases (P<0.05); 5-year survival rate after adjuvant chemotherapy It was 43.59%. The 5-year survival rate of the surgery alone group was 24.53% (P<0.05). The local recurrence rate of the postoperative adjuvant radiotherapy group was 5.88%. The recurrence rate of the surgery alone group was 33.96% (P<0.05). Conclusion The combination of early surgery combined with chemotherapy and radiotherapy should be actively carried out. This is an important means of improving the quality of life and prolonging survival.