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目的:本文研究了12例感染性休克患者甲状腺功能全套(包括T3,T4,TSH)和APACHEⅡ评分的关系。方法:甲功全套用放免法测定,APACHEⅡ评分用APACHEⅡ评分系统V 1.0分析得出。结果:血清FT3和FT4水平与发病前比较明显下降,而TSH则无明显改变。进一步分析发现,FT3、FT4水平和APACHEⅡ评分呈负相关,即血清FT3和FT4水平越低,APACHEⅡ分值越高,预后越差。结论:感染性休克时FT3和FT4水平下降,且反映了病情严重程度。动态监测血清FT3和FT4水平对预后判断可能有预测价值。
Objective: In this study, 12 cases of septic shock in patients with complete sets of thyroid function (including T3, T4, TSH) and APACHE Ⅱ score relationship. Methods: A full set of test using radioimmunoassay, APACHE Ⅱ score with APACHE Ⅱ scoring system V 1.0 analysis. Results: The levels of serum FT3 and FT4 decreased significantly compared with those before onset, while TSH did not change significantly. Further analysis found that, FT3, FT4 levels and APACHE Ⅱ score was negatively correlated, that is, the lower the serum FT3 and FT4 levels, the higher the APACHE Ⅱ score, the worse the prognosis. Conclusions: The levels of FT3 and FT4 decline during septic shock and reflect the severity of the disease. Dynamic monitoring of serum FT3 and FT4 levels may have prognostic value in predicting prognosis.