嗜麦芽寡养单胞菌 (Stenotrophomonasmaltophilia,简称Sm)是一个在环境中广泛存在的非发酵革兰阴性菌,容易在患有严重基础性疾病的住院病人中发生感染,病死率较高。Sm对大多数抗菌药物高度耐药,给临床用药带来困难。复方新诺明、多西环素是治疗Sm感染的首选药物,氟喹诺酮类、替卡西林/克拉维酸和复方新诺明联合用药有较好的抗菌活性。 Stenotrophomonas maltophilia (Sm) is a non-fermentative gram-negative bacterium that is widespread in the environment and is susceptible to infections in hospitalized patients with severe underlying diseases, with a high mortality. Sm is highly resistant to most antibacterials and poses difficulties in clinical use. Compound cotrimoxazole, doxycycline is the first choice for the treatment of Sm infection, fluoroquinolones, ticarcillin / clavulanic acid and cotrimoxazole combination has good antibacterial activity.