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目的分析2010—2015年天津市东丽区手足口病病原学分布及流行特点。方法对2010—2015年东丽区手足口病报告病例和实验室检测病例数据采用描述和分析流行病学方法对流行特征及病原检测结果进行分析。结果东丽区手足口病发病覆盖全年各个月份,呈单峰流行,6、7月为高发月份,10月为低发月份。494例标本中病原检出416例,其中柯萨奇病毒A16(Cox A16)阳性144例,肠道病毒71(EV71)阳性131例,柯萨奇病毒A6(Cox A6)阳性67例,柯萨奇病毒A10(Cox A10)阳性4例,其他肠道病毒阳性67例,混合感染3例,Cox A16感染率高于其他病原。城区病例以EV71为主,城乡接合和乡村病例以Cox A16为主,各年龄组病原主要以EV71和Cox A16为主。结论东丽区手足口病以Cox A16感染为主,其次为EV71,Cox A6及其他病原感染也不容忽视。发病高峰在6、7月,城乡接合部和农村是重点防控区域。
Objective To analyze the distribution and epidemiology of HFMD in Dongli District, Tianjin during 2010-2015. Methods Epidemiological and epidemiological analysis of reported cases of hand-foot-mouth disease and laboratory tests in Dongli District from 2010 to 2015 were conducted to analyze epidemiological characteristics and pathogen detection results. Results The incidence of hand, foot and mouth disease in Dongli District covered all months of the year with a single peak, June and July were the high-incidence months and October was the low-fat month. Of the 494 specimens, 416 were detected, of which 144 were positive for Cox A16, 131 were enterovirus 71 (EV71), 67 were Cox A6 (positive for Cox A6) 4 cases were positive for Cox A10, 67 cases were positive for other enteroviruses, 3 cases were mixed infection. The infection rate of Cox A16 was higher than other pathogens. EV71-based urban areas, urban and rural areas and rural cases of Cox A16-based, the main pathogens of all age groups with EV71 and Cox A16-based. Conclusion The Cox A16 infection of hand, foot and mouth disease in Dongli District is the most common, followed by EV71, Cox A6 and other pathogenic infections. Peak incidence in June and July, urban and rural junction and rural areas are the key prevention and control.