目的:研究海安县2004-2011年女性乳腺癌的发病率、死亡率及流行趋势。方法:根据海安县2004-2011年肿瘤登记报告数据库及人口资料,进行女性乳腺癌发病率、死亡率、累积率和截缩率分析,采用年变化率(annual percent change,APC)模型分析各种率的时间变化趋势。结果:海安县2004-2011年女性乳腺癌粗发病率、中国标化率、世界标化率分别为17.54/10万女性人口(以下发病或死亡率单位如此同,将其省略)、11.06/105和10.06/105;35~64岁截缩世标发病率和0~70岁累积发病率分别为31.61/105和1.06%,居女性恶性肿瘤全部发病病例的第5位。女性乳腺癌粗发病率、中国标化率和世界标化率APC分别为10.53%、7.40%和7.68%,其中粗发病率和世界标化率呈显著上升趋势,P值均<0.01;中国标化率呈上升趋势,P<0.05。女性乳腺癌粗死亡率、中国标化率和世界标化率分别为7.02/105、4.43/105和4.09/105;35~64岁截缩世标死亡率和0~70岁累积死亡率分别为9.59/105和0.45%。居女性恶性肿瘤全部死亡病例的第6位。女性乳腺癌粗死亡率、中国标化率和世界标化率APC分别为2.62%、1.83%和1.50%,死亡趋势相对稳定,P值均>0.05。结论:海安县2004-2011年女性乳腺癌发病率增长趋势明显,死亡率变化趋势相对稳定。 Objective: To study the incidence, mortality and prevalence of breast cancer among women in Hai'an county from 2004 to 2011. Methods: According to the database of tumor registration and the population data from 2004 to 2011 in Hai'an County, the incidence, mortality, accumulation rate and truncation rate of female breast cancer were analyzed. The annual percent change (APC) The trend of the rate of change. Results: The gross incidence of breast cancer in China from 2004 to 2011, the standardization rate of China and the world standardization rate were respectively 17.54 / 100000 female population (the same is for the following morbidity or mortality unit, omitted), 11.06 / 105 And 10.06 / 105 respectively. The incidence of contracting Worldbiao and the cumulative incidence of 0- to 70-year-old women aged 35-64 years were 31.61 / 105 and 1.06%, respectively, ranking 5th in the overall incidence of female malignant tumors. The crude incidence rate of breast cancer in China, the standardization rate in China and the world standardization rate were 10.53%, 7.40% and 7.68%, respectively. The crude incidence rate and world standardization rate showed a significant upward trend (P <0.01) The rate showed an upward trend, P <0.05. Crude breast cancer mortality rates in China, the standardization rate in China and the world standardization rates were 7.02 / 105,4.43 / 105 and 4.09 / 105 respectively; the mortality rates of the truncated world standard of 35-64 years and the cumulative mortality rates of 0-70 years were 9.59 / 105 and 0.45%. Ranking sixth in the total number of deaths from female malignant tumors. Crude breast cancer mortality rate, standardization rate of China and world standardization rate were 2.62%, 1.83% and 1.50%, respectively. The mortality trends were relatively stable with P values> 0.05. Conclusion: The incidence rate of breast cancer in women in Hai'an County increased obviously from 2004 to 2011, and the trend of mortality rate was relatively stable.