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目的 探讨妊高征患者血钙、尿素氮 (BUN)、肌酐 (Cr)水平及血BUN/Cr比值之间的相关性。方法 采用生化分析方法检测 3 11例妊高征患者的血钙、BUN、Cr及BUN/Cr比值 ,与 15 0例正常妊娠妇女及 72例非妊娠妇女对照。结果 妊高征患者血钙水平明显下降 ,与正常妊娠组、对照组比较 ,差异显著 (P <0 0 1) ,且下降程度与病情的严重程度呈正相关 ,均有显著差异 (P <0 0 1) ;血BUN、Cr水平上升 ,两者比较差异显著 (P <0 0 1) ,其升高程度反映妊高征病情的严重程度 (P <0 0 1)。结论 低血钙是妊高征的病因之一 ,血BUN、Cr水平及血BUN/Cr比值变化反映妊高征患者肾功能损害程度
Objective To investigate the correlation between serum BUN, creatinine (Cr) and blood BUN / Cr ratio in patients with pregnancy induced hypertension (PIH). Methods The serum calcium, BUN, Cr and BUN / Cr ratios in 31 cases of PIH were detected by biochemical analysis, which were compared with 150 normal pregnant women and 72 non-pregnant women. Results The level of serum calcium in patients with PIH was significantly lower than that in normal pregnancy group and control group (P <0.01), and the decrease was positively correlated with the severity of disease (P <0 0) 1). The levels of BUN and Cr in blood increased significantly (P <0.01), and the degree of increase reflected the severity of PIH (P <0.01). Conclusion Hypocalcemia is one of the causes of PIH. The changes of blood BUN and Cr levels and the ratio of blood BUN / Cr reflect the degree of renal dysfunction in patients with PIH