血红蛋白< 80g/L作为儿童发育性髋关节发育不良术后输血指征安全性的初步观察

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[目的]初步观察以血红蛋白(hemoglobin,Hb)<80 g/L作为发育性髋关节发育不良(developmental dysplasia of the hip,DDH)行髋关节切开复位联合Pemberton骨盆截骨以及股骨短缩旋转截骨术后输血指征的安全性。[方法]对在本院行切开复位联合Pemberton骨盆截骨、股骨短缩旋转截骨术的DDH患儿进行前瞻性研究,所有患儿术前及术后第1、4 d,6周行血常规检查测定Hb,配对t检验比较各时间点之间Hb的差别。以Hb<80 g/L为输注红细胞的指征,统计输血患儿比例,分析影响输血的相关因素。[结果]2010年11月~2011年8月共有52例DDH患儿行切开复位联合Pemberton骨盆截骨、股骨短缩旋转截骨术,其中男5例,女47例,平均年龄(2.43±1.37)岁。术前Hb平均为(124.35±11.13)g/L;术后第1 d平均为(101.57±10.71)g/L,较术前低(22.77±10.47)g/L(P=0.00);术后第4 d降至(93.98±8.74)g/L,较术后第1 d低(9.02±6.20)g/L(P=0.00);术后6周回升至(118.88±9.39)g/L,较术后第1 d高(17.31±9.90)g/L(P=0.00)。本组患儿均未发生失血性休克,共4例(7.69%)输血,Logistic多因素回归分析显示是否需要输血与性别、年龄、体重、侧别、脱位程度以及手术时间之间的相关性均无统计学意义。[结论]以Hb<80 g/L作为DDH切开复位联合Pemberton骨盆截骨、股骨短缩旋转截骨术后输血指征安全可行。 [Objective] To observe the effect of open reduction of hip joint combined with Pemberton pelvic osteotomy and shortening of femoral rotation with hemoglobin (Hb) <80 g / L as developmental dysplasia of the hip (DDH) Safety of transfusion indications after bone surgery. [Methods] A prospective study of DDH children undergoing open reduction combined with Pemberton pelvic osteotomy and femoral trochanter osteotomy was performed in our hospital. All children underwent preoperative and postoperative 1, 4, 6 weeks Hb was determined by routine blood tests, and paired t-test was used to compare Hb differences between time points. To Hb <80 g / L as the indication for transfusion of red blood cells, statistics of transfusion in children, analyze the factors that affect blood transfusion. [Results] A total of 52 DDH children underwent open reduction combined with Pemberton pelvic osteotomy and femoral trochanter osteotomy in November 2010 to August 2011. There were 5 males and 47 females, with an average age of 2.43 ± 1.37) years old. The mean preoperative Hb was (124.35 ± 11.13) g / L, and the average postoperative first day was (101.57 ± 10.71) g / L, lower than that of preoperative (22.77 ± 10.47) g / L (93.98 ± 8.74) g / L on the 4th day, lower than that on the first day after operation (9.02 ± 6.20) g / L (P = 0.00) Which was 17.31 ± 9.90 g / L higher than that of the first day after operation (P = 0.00). No hemorrhagic shock occurred in this group of children, a total of 4 cases (7.69%) of transfusions, Logistic regression analysis showed that the need for transfusion and sex, age, weight, side, dislocation and the correlation between the operation time No statistical significance. [Conclusion] Hb <80 g / L as DDH open reduction combined with Pemberton pelvic osteotomy, transfusions after femoral shortening rotary osteotomy is safe and feasible.
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