一氧化氮 (ＮＯ)的循环调节作用 ,不仅有扩张血管 ,而且表现出多样的作用。其活性降低 ,与血压升高与多种血管损伤的发生密切相关。一、原发性高血压与ＮＯ现已知 ,高血压时一般会有ＮＯ活性的下降 ,这不单单是因为ＮＯ合成酶 (ＮＯＳ)产生量的下降 ,还因为ＮＯ灭活增加 ,ＮＯ Nitric oxide (NO) regulates the circulation, not only dilation of blood vessels, but also shows a variety of roles. Its activity is reduced, and blood pressure is closely related to the occurrence of a variety of vascular injuries. First, the primary hypertension and NO are now known to generally have a decline in NO activity in hypertension, not only because of decreased NO synthase (NOS) production, but also because of increased NO inactivation, NO