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近年来,凝血和纤溶系统与脑血管疾病的关系日益为人们所关注,有关脑血管疾病时体内凝血系统被激活和反应性纤维活性增强的报道不断增加,有一部分临床和实验亦证明了凝血系统在缺血性脑卒中的发病中起着重要作用[1],而不断推出的敏感检测方法,又为精确分析凝血和纤溶的相关因素提供了有力的依据,本文就此作一综述。1 检测凝血和纤溶系统指标的进展 凝血系统和纤溶系统有相似的瀑布式激活过程,正常情况下,人体凝血纤溶系统处于动态平衡,起着保持血管完整性和疏通血流通道的双重作用。在纤维蛋白原转化为纤维蛋白的过程中,凝血酶起着主要的促
In recent years, blood coagulation and fibrinolysis system and the relationship between cerebrovascular disease is increasingly concerned about the cerebrovascular disease in vivo activation of the coagulation system and increased activity of reactive fibers reported increasing, there are some clinical and experimental evidence of coagulation The system plays an important role in the pathogenesis of ischemic stroke [1]. However, the continuous introduction of sensitive detection methods provides a powerful basis for the accurate analysis of the relevant factors of coagulation and fibrinolysis. This article reviews this issue. 1 coagulation and fibrinolytic system to detect the progress of indicators coagulation system and fibrinolysis system has a similar waterfall activation process, under normal circumstances, the body’s coagulation and fibrinolysis system in a dynamic equilibrium, plays to maintain vascular integrity and clear the blood flow channel dual effect. Thrombin plays a major role in the conversion of fibrinogen to fibrin