本研究采用“3414”不完全正交回归设计方案,分析了氮、磷、钾肥不同水平对苦豆子产量及苦参碱含量的影响。结果表明:1)N+P+K、N+P、N+K三种施肥组合与苦豆子产量相关性最大,单施N、P、K和P+K对其影响较小。2)复合施肥N、P2O5、K2O用量分别为134.85、91.0、59.9kg/hm2时苦豆子产量最高,约为2 016.75kg/hm2。3)综合考虑各药用部位苦参碱含量,施肥量的最优范围为N 125～180kg/hm2、P2O580～90kg/hm2、K2O10～45kg/hm2。 In this study, “3414 ” incomplete orthogonal regression design was used to analyze the effects of different levels of nitrogen, phosphorus and potassium fertilizers on the yield of Sophora alopecuroides and matrine content. The results showed that: 1) The combination of N + P + K, N + P and N + K had the highest correlation with the yield of Sophora alopecuroides, but the effect of N, P, K and P + K was little. 2) The yield of Sophora alopecuroides with the compound fertilizers N, P2O5 and K2O was 134.85, 91.0 and 59.9 kg / hm2 respectively, which was about 2 016.75kg / hm2.3) Considering the matrine content and the amount of fertilizer The optimum range is N 125 ~ 180kg / hm2, P2O580 ~ 90kg / hm2, K2O10 ~ 45kg / hm2.