慢性阻塞性肺疾病(COPD)具有气流受限部分可逆特征,系因气道慢性炎症和重构所致,可伴有全身炎症表现和肺外并存疾病。慢性全身性炎症可能导致COPD和并存疾病的共同发病。抗炎治疗亦可作用于全身性炎症和肺外并存疾病,而治疗并存疾病亦有助于COPD的恢复。因此,治疗COPD应同时评估并存疾病,采用综合治疗措施。 Chronic obstructive pulmonary disease (COPD) has a partially reversible air flow confinement characteristics, due to chronic airway inflammation and remodeling, may be associated with systemic inflammatory manifestations and extra-pulmonary disease. Chronic systemic inflammation may lead to the co-occurrence of COPD and co-morbidities. Anti-inflammatory treatment can also affect systemic and extra-pulmonary disease, and the treatment of coexisting diseases also contributes to the recovery of COPD. Therefore, the treatment of COPD should simultaneously evaluate the coexistence of disease, the use of comprehensive treatment.