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三十多年来,我国在筛选抗病毒中草药和方剂方面做了大量的工作。虽发现一定数量的药物在体外能抑制病毒的生长繁殖,但在体内不一定有效。现在世界各国在投药方法上有不少创新,其中定向给药最为人注目。选择性地定向地把有效药物直接输送至病灶,可以大大提高疗效。下面着重就病毒的特点与投药方法及剂型机理的关系作一些探讨。一、抗病毒感染要求向免疫系统定向给药在大量复制出来的新病毒破坏健康细胞之前,阻断病毒的大量复制和免疫损害,可有效地抵御病毒感染。
For more than 30 years, China has done a lot of work in screening antiviral herbal medicines and formulas. Although it has been found that a certain number of drugs can inhibit the growth and reproduction of viruses in vitro, they are not necessarily effective in vivo. Nowadays, there are many innovations in the methods of administering drugs in the countries of the world, of which targeted drugs are the most noticeable. Selectively targeted delivery of effective drugs directly to the lesion can greatly improve the efficacy. The following focuses on the relationship between the characteristics of the virus and the method of drug administration and dosage mechanism. First, the anti-viral infection requires directed administration to the immune system. Before a large number of replicated new viruses destroy healthy cells, blocking the virus’s massive replication and immune damage can effectively resist the virus infection.