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本文采用ELISA法测定了82例冠心病(CHD)患者和70例健康人血清脂蛋白α[Lp(α)]及血脂水平。结果显示:冠心病组Lp(α)水平明显高于正常对照组,差异显著(P<0.05);高密度脂蛋白胆固醇(HDL—C)水平明显低于对照组,差异显著(P<0.05)。血清甘油三酯(TG)水平及总胆固醇(TC)水平与对照组比较,差异均无显著性(P>0.05)。Lp(α)与其它血脂间无明显相关性(P>0.05)。冠心病组Lp(α)的异常检出率为57.7%,是对照组的2.12倍(P<0.05)。提示:Lp(α)与冠心病发病密切相关,是冠心病重要的独立危险因素。
In this paper, the serum levels of lipoprotein α (Lpα) and blood lipids in 82 patients with coronary heart disease (CHD) and 70 healthy people were measured by ELISA. The results showed that the level of Lp (α) in coronary heart disease group was significantly higher than that in the normal control group (P <0.05), while the level of HDL-C in the coronary heart disease group was significantly lower than that of the control group (P <0.05) . Serum triglyceride (TG) and total cholesterol (TC) levels compared with the control group, the difference was not significant (P> 0.05). There was no significant correlation between Lp (α) and other lipids (P> 0.05). The detection rate of Lp (α) in coronary heart disease group was 57.7%, which was 2.12 times that of the control group (P <0.05). Tip: Lp (α) is closely related to the pathogenesis of coronary heart disease and is an important independent risk factor for coronary heart disease.