本文对各型HBV感染者50例的同份血清作了Pre-S_2蛋白与HBeAg、HBV-DAN检测,并与同期肝组织内HBcAg,HBsAg的关系进行了初步研究。50例HBV感染者均系1984～1988年收治的患者,其中重型肝炎9例,慢性活动性肝炎(CAH)18例,无症状HBsAg携带者(AsC)18例,甲乙型肝炎重叠感染者5例。 检测方法:(1)血清Pre-S_2蛋白ELISA检测药盒及血清HBV-DVA(斑点杂交试验)药盒均(?)北京医科大学肝病研究所提供。(2)HBeAg(?)-HBe药盒由302医院免疫室提供(ELISA) Pre-S 2 protein, HBeAg and HBV-DNA were detected in the same sera of 50 cases of HBV infection. The relationship between HBsAg, HBsAg and HBcAg in liver tissue was also studied. Fifty patients with HBV infection were admitted to our hospital from 1984 to 1988, including 9 cases of severe hepatitis, 18 cases of chronic active hepatitis (CAH), 18 cases of asymptomatic HBsAg carriers (AsC), 5 cases of hepatitis A and B . Detection methods: (1) serum Pre-S_2 protein ELISA kit and serum HBV-DVA (dot blot hybridization test) kit (?) Beijing Medical University Liver Institute. (2) HBeAg (?) - HBe kit provided by the 302 Hospital Immunization Room (ELISA)