以腹膜延长阴道提高年轻宫颈癌患者术后生活质量的临床研究

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目的:探讨年轻宫颈癌患者采用腹膜延长阴道的临床意义和术后放疗对性功能的影响;方法:选择2007年以来住院年龄<45岁资料完整、随访可靠的宫颈癌患者73例分为两组,研究组41例行宫颈癌根治术加一侧或双侧卵巢移位加以腹膜延长阴道术,术前、术后3、6、12个月测性激素;对照组32例行宫颈癌根治术,或加一侧或双侧卵巢移位。两组术后高危因素者均行辅助放疗。结果:研究组术后测量阴道长度较对照组长,差异有统计学意义(P<0.01);放疗后阴道较放疗前缩短,但仍较对照组长,差异有统计学意义(P<0.01);研究组术后性生活满意度优于对照组。研究组15例行放疗,放疗后测FSH、LH明显升高,与放疗前差异有统计学意义(P<0.01),提示放疗后卵巢衰竭明显;未行放疗者卵巢功能无明显变化。结论:年轻宫颈癌患者采用腹膜延长阴道明显提高术后性生活质量,但术后行放疗是影响性功能的不利因素。 Objective: To investigate the clinical significance of peritoneal extension of vagina in young patients with cervical cancer and the effect of postoperative radiotherapy on sexual function.Methods: The data of 73 hospitalized patients with cervical cancer who were hospitalized 45 years old since 2007 were collected and divided into two groups , The study group of 41 patients underwent radical cervical cancer plus one or both sides of the ovarian transposition and peritoneal extension of vaginal surgery, preoperative and postoperative 3,6,12 months to test the hormone; control group 32 cases of cervical cancer radical surgery, Or add one or both ovarian transposition. Two groups of postoperative risk factors were assisted radiotherapy. Results: The length of the vagina measured by the study group was longer than that of the control group (P <0.01). The vaginal length of the vagina was shorter than that of the control group after radiotherapy, but the difference was statistically significant (P <0.01) ; Study group postoperative sexual satisfaction than the control group. The study group 15 cases of radiotherapy, radiotherapy FSH, LH was significantly elevated, and before radiotherapy was statistically significant (P <0.01), suggesting that ovarian failure after radiotherapy significantly; no radiotherapy no significant change in ovarian function. Conclusion: The young patients with cervical cancer with prolonged peritoneal vaginal prolongation significantly improve the quality of postoperative sexual life, but postoperative radiotherapy is an unfavorable factor affecting sexual function.
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