目的了解影响阳春市艾滋病抗病毒治疗依从性的因素并提出应对策略。方法对阳春市全部正在接受抗病毒治疗的126名艾滋病患者进行匿名问卷调查,调查内容包括患者的人口学特征、服药知情和药物漏服原因。采用描述性流行病学方法对患者的服药依从性及影响因素进行分析。结果 126例患者中,服药依从性≥95%的患者为59.5%(75/126)。不同配偶检测情况、是否与子女同住、服药后身体自我感觉和服药前后CD4情况患者服药依从性差异有统计学意义(P<0.05),而不同性别、年龄、婚姻、文化程度、治疗时间和服药时病程患者服药依从性差异无统计学意义(P>0.05)。漏服药物的主要原因有忘记吃药(43.5%)和不愿别人知道自己吃药(15.7%)。结论阳春市接受抗病毒治疗的病人服药依从性仅为59.5%,影响依从性的主要因素是家庭和服药后效果。应当加强病人和家人抗病毒治疗相关知识的宣传,告知病人治疗过程中的注意事项和按照医嘱服药的重要性,通过对病人和家人的随访、提醒,提高他们的服药知识,从而提高病人的服药依从性。 Objective To understand the factors that affect the compliance of HIV antiviral therapy in Yangchun and to put forward the countermeasures. Methods A total of 126 AIDS patients undergoing antiviral therapy in Yangchun were surveyed anonymously. The investigation included demographic characteristics, medical knowledge and causes of drug leakage. Descriptive epidemiological methods were used to analyze the patient’s medication compliance and influencing factors. Results Of the 126 patients, 59.5% (75/126) had medication compliance ≥95%. There were significant differences (P <0.05) in taking medication between CD4 (superscript +) patients before and after self-perception and taking medication before taking drugs, but different gender, age, marriage, education, treatment time and There was no significant difference in medication compliance between the two groups (P> 0.05). The main reasons for missed medication are forgetting to take medicine (43.5%) and not want others to know that they take medicine (15.7%). Conclusion The compliance rate of patients receiving anti-virus therapy in Yangchun was only 59.5%. The main factors influencing compliance were family and post-medication effects. Patients and their families should be strengthened awareness of anti-viral treatment of information, to inform patients of treatment considerations and the importance of medication according to doctor’s orders, follow-up of patients and their families, to remind and enhance their medication knowledge, thereby enhancing the patient’s medication Compliance.