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目的了解丙酸氟替卡松鼻喷雾剂联合舒利迭吸入剂对过敏性鼻炎-哮喘综合症患者的治疗效果。方法 A组30例,给予丙酸氟替卡松鼻喷雾剂,早上每个鼻孔各喷2次,晚上每个鼻孔各喷3次。B组30例,给予吸入舒利迭50/250。C组30例,在吸入舒利迭治疗基础上,同时给予丙酸氟替卡松鼻喷雾剂治疗,早上每个鼻孔各2喷,晚上每个鼻孔各3喷。治疗时间为3个月,每隔3周随访1次,记录哮喘症状ACT评分及鼻炎症状评分、治疗前和治疗后的肺功能状况。结果 A、B、C三组对哮喘症状及肺通气情况都有显著改善,治疗前后均有显著差异(P<0.05),且B、C组高于A组,两组间比较差异有统计学意义(P<0.05),但在改善鼻部症状记分方面A组和C组明显优于B组(P<0.05)。结论联合治疗过敏性鼻炎和支气管哮喘比单纯治疗支气管哮喘或单纯治疗过敏性鼻炎更能有效的提高临床疗效,更快控制哮喘,改善患者症状。
Objective To understand the therapeutic effect of fluticasone propionate nasal spray combined with seretide in patients with allergic rhinitis-asthma syndrome. Methods A group of 30 patients were given fluticasone propionate nasal spray, spray each nostril two times in the morning and spray three times in each nostril at night. B group 30 cases, given inhaled Seretide 50/250. In group C, 30 patients were treated with inhaled seretide and treated with fluticasone propionate nasal spray. In the morning, each nostril was sprayed for 2 and sprayed for 3 nostrils at night. The treatment time was 3 months and followed up every 3 weeks. The ACT score of asthma symptoms, rhinitis symptom score, pulmonary function status before and after treatment were recorded. Results The symptoms of asthma and pulmonary ventilation were significantly improved in groups A, B and C, with significant difference before and after treatment (P <0.05), and those in groups B and C were higher than those in group A, with statistically significant differences between the two groups (P <0.05), but A group and C group were significantly better than B group in improving nasal symptom score (P <0.05). Conclusions The combined treatment of allergic rhinitis and bronchial asthma is more effective in improving the clinical curative effect than the simple treatment of bronchial asthma or simple treatment of allergic rhinitis, and the control of asthma is faster and the symptom of the patient is improved.