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目的研究甲氨蝶呤(MTX)联合米非司酮对宫外孕保守治疗的临床疗效。方法选取宫外孕患者40例,随机分为观察组和对照组,各20例,观察组给予甲氨蝶呤联合米非司酮治疗,对照组给予甲氨蝶呤治疗,比较两组宫外孕治疗效果。结果与对照组相比,观察组患者治愈率明显升高,治疗后相比治疗前患者β-人绒毛膜促性腺激素显著降低,盆腔包块变小,腹痛消失时间缩短,不良反应发生率降低,差异有统计学意义(P<0.05)。结论甲氨蝶呤(MTX)联合米非司酮应用于宫外孕治疗,临床效果显著、安全可靠。
Objective To study the clinical efficacy of methotrexate (MTX) combined with mifepristone in the conservative treatment of ectopic pregnancy. Methods Forty patients with ectopic pregnancy were randomly divided into observation group and control group, with 20 cases each. Methotrexate and mifepristone were given to the observation group while methotrexate was given to the control group. Ectopic pregnancy was compared between the two groups. Results Compared with the control group, the cure rate of the observation group was significantly increased, the β-human chorionic gonadotropin was significantly decreased, the pelvic mass was smaller, the disappearance of abdominal pain was shorter and the incidence of adverse reactions was lower , The difference was statistically significant (P <0.05). Conclusion Methotrexate (MTX) combined with mifepristone in the treatment of ectopic pregnancy, the clinical effect is significant, safe and reliable.