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本文运用细胞化学定位、定性、定量技术探讨了慢性肾炎外周血淋巴细胞及单核细胞的ANAE变化及其与中医辨证的关系。发现肾阳虚组淋巴细胞ANAE阳性率及点状型百分率显著低于肾阴虚组(P<0.05、0.01),弥散型百分率则高于肾阴虚组(P<0.05),其单核细胞ANAE含量亦显著低于肾阴虚组(P<0.001);慢性肾炎组与正常人比较,各项指标均有不同程度的显著性差异。最后初步探讨了其机理及临床意义。
In this study, the changes of ANAE in peripheral blood lymphocytes and monocytes of chronic nephritis and their relationship with TCM syndrome differentiation were investigated using cytochemical localization, qualitative and quantitative techniques. It was found that the positive rate and dot percentage of ANAE in lymphocytes of kidney-yang deficiency group were significantly lower than those in kidney-yin-deficiency group (P<0.05, 0.01), and the percentage of diffuse type was higher than that in kidney-yin deficiency group (P<0.05). The content of ANAE was also significantly lower than that of kidney yin deficiency group (P<0.001). Compared with the normal people, the chronic nephritis group had significant differences in various indexes. Finally, the mechanism and clinical significance of this study were initially discussed.