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Objective In order to solve the problem of the decreased portal inflow, decreased metabolic function and dangerous varicosity in portal hypertension, a pulsation-type portal pump was prepared and used in the treatment experiment of canine model for portal hypertension, which was made by thread embolization in the portal vein. Methods Tow threads which were injected into the two branches of the portal vein would lead to portal hypertension after 2 weeks. A pulsation-type portal pump was made of a silica rubber balloon and a T-shaped silica rubber tube. At the 2 tips of the T-shaped tube, two valves allowed the blood to flow in one direction. Two plates on both side of the balloon made the balloon pulsate constantly. One plate made of stainless steel was fixed on one side of the balloon while the other made of a piece of strong magnetic steel were fixed on the other side. The power was supplied by a low frequency alternating magnetic field that was placed outside the abdomen. The T-shaped tip of the pump was then placed into the portal vein at the point above the major collateral branches. The blood pressure and flow of the portal system and the liver metabolic functions were measured. Results After pump working, the portal blood pressure above the pump increased from ( 2.969±0.412)kPa to (4.802±0.696)kPa, whereas the portal pressure below the pump decreased from ( 3.077± 0.301)kPa to ( 1.764± 0.421)kPa,and the blood inflow of the liver increased from ( 0.270± 0.028)L·min -1 to (0.396±0.025) L·min -1. The pressure of the splenic vein decreased from ( 3.548± 0.392)kPa to ( 2.009± 0.333)kPa and the pressure of the gastric fundal vein decreased from ( 3.459± 0.323)kPa to ( 1.891± 0.461)kPa. The ICGK increased from ( 0.092± 0.009) to ( 0.151± 0.013) while the ICGR 15 decreased from 19.03± 8.50 to 9.04± 2.50.Conclusion The pulsation-type portal pump significantly increased the blood inflow and the metabolic function of the liver, and decreased the blood pressure of the portal system. The design of the pump structure and the power supply were reasonable and skillful. More research work is needed to make the pump to be placed safer and longer.
Objective In order to solve the problem of the decreased portal inflow, decreased metabolic function and dangerous varicosity in portal hypertension, a pulsation-type portal pump was prepared and used in the treatment experiment of canine model for portal hypertension, which was made by thread embolization in the portal vein. Methods Tow threads which were injected into the two branches of the portal vein would lead to portal hypertension after 2 weeks. A pulsation-type portal pump was made of a silica rubber balloon and a T-shaped silica rubber tube. At the 2 tips of the T-shaped tube, two valves allowed the blood to flow in one direction. Two plates on the balloon to the balloon pulsate constantly. One plate made of stainless steel was fixed on one side of the balloon while the other made of a piece of strong magnetic steel were fixed on the other side. The power was supplied by a low frequency alternating magnetic field that was placed outside the abdomen. The T-sha ped tip of the pump was then placed into the portal vein at the point above the major collateral branches. The blood pressure and flow of the portal system and the liver metabolic functions were measured. Results After pump working, the portal blood pressure above the pump increased from (2.969 ± 0.412) kPa to (4.802 ± 0.696) kPa, the the portal pressure below the pump decreased from (3.077 ± 0.301) kPa to (1.764 ± 0.421) kPa, and the blood inflow of the liver increased from ± 0.028) L · min -1 to (0.396 ± 0.025) L · min -1. The pressure of the splenic vein decreased from (3.548 ± 0.392) kPa to (2.009 ± 0.333) kPa and the pressure of the gastric fundal nerve The ICG increased from (0.092 ± 0.009) to (0.151 ± 0.013) while the ICGR 15 decreased from 19.03 ± 8.50 to 9.04 ± 2.50. Conlusion The pulsation-type portal (3.459 ± 0.323) kPa to pump significantly increased the blood inflow and the metabolic function of the liver, and dThe design of the pump structure and the power supply were reasonable and skillful. More research work is needed to make the pump to be placed safer and longer.