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目的 评价心肌钙蛋白T (cTnT)在急性冠状动脉综合征的诊断价值。方法 收入急诊ICU的急性冠状动脉综合征病人分为 :AMI组和UAP组 ,抽取肘部静脉血 1ml立即注入肝素抗凝试管中 ,混匀。用德国宝灵曼中国有限公司提供的肌钙蛋白T灵敏检测试纸条进行定性检查。同时用放免分析方法测定血清CK、CK MB及AST。结果 AMI组cTnT阳性率为 70 6 % ,UAP组阳性率 16 7% ,两组阳性率对比有显著性差异性 (P <0 0 1)。结论 cTnT是反映心肌细胞损伤的灵敏性、特异性均较好的生化指标 ,cTnT定性检测可用于ACS早期鉴别诊断 ,其临床意义优于血清CK、CK MB及AST。
Objective To evaluate the diagnostic value of cardiac troponin T (cTnT) in acute coronary syndrome. Methods Patients with acute coronary syndrome who were admitted to emergency ICU were divided into two groups: AMI group and UAP group. 1ml elbow venous blood was drawn into heparin anticoagulation tube immediately and mixed well. Qualitative examination of Troponin T Sensitive Test Strips provided by Bauhinia Germany GmbH, Germany. Meanwhile, serum CK, CK MB and AST were measured by radioimmunoassay. Results The positive rate of cTnT in AMI group was 70.6%, while the positive rate in UAP group was 16.7%. There was significant difference between the two groups in the positive rate of cTnT (P <0.01). Conclusions cTnT is a biochemical index that reflects the sensitivity and specificity of cardiomyocyte injury. CTnT qualitative detection can be used in the early differential diagnosis of ACS. The clinical significance of cTnT is better than that of serum CK, CK MB and AST.