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目的:观察中西医治疗高催乳素血症不孕症患者43例的的临床疗效。方法:将86例高催乳素不孕症患者,随机分为对照组、治疗组两组。对照组43例患者给予溴隐亭治疗,治疗组加服自拟疏肝补肾汤,连服3个月。观察两组患者的临床疗效、性激素[包括催乳素(PRL)、黄体生成素(LH)、卵泡刺激素(FSH)、雌二醇(E2)、孕酮(P)、睾酮(T)]水平,临床症状积分及妊娠情况等。结果:治疗组、对照组的临床疗效95.3%、79.1%;治疗后两组均可降低PRL水平,提高E2、P水平(P>0.05);但治疗组在临床症状改善方面明显优于对照组(P<0.05);治疗组妊娠率显著高于对照组(P<0.05)。结论:中西医治疗高催乳素血症不孕症具有良好的疗效,可改善患者临床症状,提高妊娠率,减少溴隐亭的不良反应,值得临床推广应用。
Objective: To observe the clinical curative effect of treating 43 cases of infertility with hyperprolactinemia by Chinese and Western medicine. Methods: 86 cases of hyperprolactinemia infertility were randomly divided into control group and treatment group. Control group, 43 patients given bromocriptine treatment, the treatment group plus self Shugan Bushen decoction, and even for 3 months. To observe the clinical efficacy of two groups of patients, sex hormones [including prolactin (PRL), luteinizing hormone (LH), follicle stimulating hormone (FSH), estradiol (E2), progesterone (P), testosterone , Clinical symptom scores and pregnancy status. Results: The clinical curative effect of the treatment group and the control group was 95.3% and 79.1% respectively. After treatment, the PRL level and the level of E2 and P in both groups were decreased (P> 0.05). However, the treatment group was significantly better than the control group in improving clinical symptoms (P <0.05). The pregnancy rate in the treatment group was significantly higher than that in the control group (P <0.05). Conclusion: Integrative treatment of hyperprolactinemia with infertility has a good effect, which can improve clinical symptoms, improve pregnancy rate and reduce the adverse reactions of bromocriptine, worthy of clinical application.