论文部分内容阅读
采用整体和离体相结合方法、观察了氯氰菊酯对大鼠肝脏磷酸化酶ａ、Ｃａ２＋－ＡＴＰ酶活力的影响。整体实验表明．氯氰菊酯染毒后可使大鼠肝脏磷酸化酶ａ明显升高．Ｃａ２＋－ＡＴＰ酶含量明显下降，与对照组相比有显著性差异（Ｐ＜０．０５或Ｐ＜０．０１）．且存在明显的剂量－效应关系、而离体实验表明．氯氰菊酯也可引起大鼠肝线粒体、微粒体Ｃａ２＋－ＡＴＰ酶显著下降．也存在明显的剂量－效应关系．
The effects of cypermethrin on the activity of phospholipase a and Ca2 + -ATP in liver were observed by a combination of whole and in vitro methods. The overall experiment shows. After exposure to cypermethrin, rat liver phosphorylase can be significantly increased. Ca2 + -ATP enzyme content decreased significantly compared with the control group (P <0.05 or P <0.01). And there is a clear dose-response relationship, while in vitro experiments show. Cypermethrin can also cause rat liver mitochondria, microsomal Ca2 + -ATPase decreased significantly. There is also a clear dose-response relationship.