人体中肝脏的物质代谢极为旺盛。因此肝脏对维持机体代谢内环境的稳定性甚重要。肝细胞的储备功能很强。一般只要有20％的正常肝细胞即能维持机体内环境的稳定。肝脏的功能是多方面的,特别是某些物质代谢只有肝脏具备这种功能,如酮体形成、尿素合成以及某些内分泌激素的分解代谢。肝脏分解的内分泌激素见表1,且分解过程亦不同(表2),如胰岛素的破坏可能包括胰岛素-依赖酶谷胱甘肽胰岛素转氢酶的降解,别的蛋白质激素可由其他蛋白酶和肽酶降解,不同的降解过程涉及不同肝病细胞不同的形态部位,如细胞表面、微粒体、胞浆等。全身物质代谢在肝脏疾病中可发生多种变化, The body’s metabolism of the liver is extremely strong. Therefore, the liver to maintain the stability of the metabolic environment is very important. Hepatocyte reserve function is very strong. Generally, as long as 20% of normal liver cells can maintain the stability of the body environment. The function of the liver is multifaceted, and in particular, the metabolism of some substances is only the liver that has this function, such as ketone body formation, urea synthesis, and the catabolism of certain endocrine hormones. The breakdown of endocrine hormones in the liver is shown in Table 1, and the decomposition process is also different (Table 2), such as the destruction of insulin may include the degradation of insulin-dependent enzyme glutathione insulin transhydrogenase, other protein hormones by other proteases and peptidases Degradation, different degradation process involves different liver cells in different morphological parts, such as cell surface, microsomes, cytoplasm and so on. Whole body metabolism in the liver disease can occur a variety of changes,