论文部分内容阅读
输血后非甲非乙型肝炎的主要病原为HGV,本文报道6只猩猩实验感染的后果和血清学及病毒学检测的数据。6只猩猩中有甲型肝炎抗体者3只,而6只中有乙型肝炎抗体者4只,有HBsAg者1只。后5只动物过去曾用于甲型肝炎、乙型肝炎试验,仅1只未曾作过任何肝炎试验,血清学、肝活检组织学和组化检验所有结果均阴性。 6只猩猩接种已证明有HCV的血液或血制品Ⅷ因子,6只均发生急性丙型肝炎,其中2只演变为慢性丙型肝炎。急性期发生于接种后7～16周,可见转氨酶升降曲线和峰值。
The main cause of non-A, non-B hepatitis after transfusion is HGV. The results of experimental infection in 6 chimpanzees and serological and virological data were reported in this paper. Three chimpanzees had hepatitis A antibodies, while six of them had four hepatitis B antibodies and one had HBsAg. The last five animals were used in the past for Hepatitis A and Hepatitis B tests. Only one patient had not had any hepatitis test. All the results of serology, liver biopsy and histochemistry were negative. Six chimpanzees had been vaccinated with blood or blood products that had been proven to have HCV, and all six developed acute hepatitis C, two of which developed chronic hepatitis C. Acute phase occurred 7 to 16 weeks after inoculation, showing elevated transaminase curve and peak.