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目的探讨肝前脂肪厚度与多囊卵巢综合征(PCOS)不孕症患者胰岛素抵抗相关指标的关系,为PCOS不孕症的治疗提供相关依据。方法对91例PCOS不孕症患者行超声检测肝前脂肪厚度,并测量身高、体质量、腰围(WC)、臀围(HC)等指标,检测性激素、胰岛素等核医学指标;检测血脂、血糖等生化指标,分析肝前脂肪厚度与上述指标间的关系。结果肝前脂肪厚度与体质量、体重指数(BMI)、WC、HC等人体测量值呈正相关(P<0.05),与身高无明显相关(P>0.05);与空腹胰岛素、血糖、尿酸、胰岛素抵抗指数等呈正相关(P<0.05),与高密度脂蛋白呈负相关(P<0.05);与性激素、甲状腺功能、总胆固醇、甘油三酯、低密度脂蛋白及其他肝肾功能指标无明显相关(P>0.05)。结论肝前脂肪厚度在PCOS不孕症患者中与胰岛素抵抗有关的指标有一定的相关关系;在临床诊治该类患者时应全面评估,以提高妊娠率及改善妊娠结局。
Objective To investigate the relationship between pre-hepatic fat thickness and insulin resistance in patients with polycystic ovary syndrome (PCOS) infertility and to provide relevant evidence for the treatment of PCOS infertility. Methods Ninety-one patients with PCOS were enrolled in this study. The pre-hepatic fat thickness was measured by ultrasound. The height, body mass, waist circumference (WC), hip circumference (HC) and other indexes were measured to detect the nuclear medicine indexes such as sex hormones and insulin. And other biochemical indicators, analysis of pre-hepatic fat thickness and the relationship between the above indicators. Results There was a positive correlation between prethrombocyte thickness and body mass, body mass index (BMI), WC, HC and other human body measurements (P <0.05), but not with body height (P> 0.05) (P <0.05), negatively correlated with high density lipoprotein (P <0.05), but no significant correlation with sex hormones, thyroid function, total cholesterol, triglyceride, low density lipoprotein and other indicators of liver and kidney Related (P> 0.05). Conclusion Pre-hepatic fat thickness has some correlation with insulin resistance in patients with PCOS infertility. It should be fully evaluated in clinical diagnosis and treatment to improve pregnancy rate and improve pregnancy outcome.