米非司酮配合利凡诺尔用于中期妊娠引产的疗效观察

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目的探讨米非司酮联合利凡诺尔用于中期妊娠引产的疗效。方法选取2014年1月-2016年10月医院收治的因不同原因需接受引产的中期妊娠孕妇100例作为研究对象,采取单盲随机分组法随机将孕妇分为观察组和对照组,每组50例,对照组采用单一利凡诺尔引产,观察组采用利凡诺尔与米非司酮联合引产,比较2组孕妇的引产成功率、分娩发动时间、出血量、胎盘胎膜残留率、宫颈裂伤率。结果观察组孕妇的引产成功率明显高于对照组孕妇,且观察组孕妇的分娩发动时间明显短于对照组,差异均有统计学意义(P<0.05)。观察组孕妇的引产后出血量少于对照组,胎盘胎膜残留率及宫颈裂伤率均低于对照组,差异均有统计学意义(P<0.05)。结论采用利凡诺尔与米非司酮联合用药对中期妊娠孕妇实施引产具有良好的引产效果,可缩短引产时间,减少胎盘胎膜残留、宫颈裂伤及出血的发生。 Objective To investigate the efficacy of mifepristone combined with rivanol for inducing labor in mid-term pregnancy. Methods A total of 100 middle-term pregnant women who were admitted to our hospital from January 2014 to October 2016 due to different causes were enrolled in this study. Pregnant women were randomly divided into observation group and control group by single-blind randomized grouping method For example, the control group received a single Rivinol induction of labor, the observation group with rivanol and mifepristone induction of labor, compared two groups of pregnant women, induction of labor success rate, labor onset, bleeding, residual fetal membranes rate, cervical laceration rate. Results The success rate of induction of labor in pregnant women in observation group was significantly higher than that of pregnant women in control group, and the onset time of labor in observation group was significantly shorter than that in control group (P <0.05). In the observation group, the amount of bleeding after induction of labor was less than that of the control group, the residual rate of fetal membranes and the rate of cervical laceration were lower than those in the control group, with statistical significance (P <0.05). Conclusions The combination of Rivanol and mifepristone for induction of labor in mid-term pregnant women has a good effect of induction of labor can shorten the time of induction of labor, reduce the residual placental membranes, cervical laceration and bleeding.
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